Spironol-25 Tablet is a diuretic medication used to treat heart failure and high blood pressure, reducing swelling and hypokalemia. It can be taken with or without food, and should be taken consistently to maximize benefits. It can be taken with food to reduce side effects and early in the day to prevent nighttime toileting. Lifestyle changes, such as regular exercise and diet, may increase its effectiveness. Common side effects include nausea, vomiting, dizziness, and breast tenderness. It is important to inform your doctor about any kidney, liver, or heart disease history, and inform your healthcare team about other medications. It should only be used if needed during pregnancy and breastfeeding.