Sitagliptin-GM 1/1000 tablet is a combination of three medications used to lower blood glucose levels in type 2 diabetes patients. It is best taken with food and should be taken regularly, at the same time each day. The dose and duration are determined by the patient's condition and response. It is part of a treatment program that includes a healthy diet, regular exercise, and weight reduction. Common side effects include hypoglycemia, headache, nausea, diarrhea, abdominal pain, constipation, and vomiting. It is not recommended for individuals with type 1 diabetes, metabolic acidosis, active bladder cancer, or pregnant or breastfeeding women.