Nolltrim cream is an antifungal medication used to treat fungal vaginal infections, causing burning, itching, and abnormal discharge. It destroys fungal cell membranes and is for external use only, advised by a doctor. It is best used at night and should be cleaned before and after use. Common side effects include vaginal burning sensation and irritation. If side effects persist, consult a doctor. Nolltrim is not likely to affect other medications, but if you have used a similar medication and have had an allergic reaction, consult your doctor.