Metopole-Trio 50 Tablet is a combination of medications used to treat hypertension, lowering blood pressure and reducing the risk of heart attacks and strokes. It can be taken with food or at the same time daily, and should be continued as advised by a doctor. Side effects include nausea, throat infection, back pain, and ankle swelling. Regular monitoring of blood pressure, kidney function, blood sugar level, and electrolytes is advised. Pregnant or breastfeeding women should consult their doctor before taking this medication.