Clindinol-M 50 SR Tablet is a medication used to treat hypertension, a combination of two medications that helps control blood pressure and prevent future heart attacks and strokes. It can be taken with food or at the same time daily, and should be continued as advised by a doctor. Side effects include headache, ankle swelling, slow heart rate, nausea, and dizziness. Regular monitoring of blood pressure, kidney function, blood sugar level, and electrolytes is recommended. Consult a doctor if you have liver or kidney problems, pregnant or breastfeeding women, or have other heart conditions.